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Read this article about cancer research published by the New England Journal of Medicine.


From the New England Journal of Medicine Jan 14, Vol. 340, No. 2, 77 - 168
Calcium Supplements for the Prevention of Colorectal Adenomas (colon cancer)
J.A. Baron M.D., and Others

See definitions of Colorectal and Adenomas in our dictionary of "buzz words"

Science and Research

In the research outlined below, you will find statements, explanations and simple revelations to the amazing properties of the humble mineral Calcium. This truth comes to you though documents created by some of the most well known and prestigious scientists and publications in the world. The critical role that calcium plays in our health is nothing short of astounding. We trust that you will find this collection both helpful and a source of knowledge about biological calcium.

The scientific evidence that calcium is the key to good and long health is overwhelming. One does not have to be a rocket scientist to read simple articles in reputable newspapers, magazines and the doctor’s own journals that are all saying that disease can be cured by diet.

- Robert Barefoot


The life so short, the craft so long to learn.
Hippocrates


New York Times
"Calcium Takes Its Place As a Superstar of Nutrients"
October 13, 1998

"It is the primary building block of our teeth and bones. It provides the electrical energy for the heart to beat and for all muscle movement. It is the calcium ion that is responsible for feeding every cell. Without calcium, DNA cannot replicate itself. As a result, low calcium means low body repair and premature aging. But, most important of all, calcium controls the pH of the body."


"How a Mineral Can Vitalize Your Health", by Dr. James
K. Van Fleet, in the book Magic of Catalytic Health Vitalizers, 1980, Parker Publishing.

"According to nutritional authorities, the American diet is more lacking in calcium than in any other essential food. Dr. Henry C. Sherman, the noted biochemist, has stated in effect that the prime period of human life could be extended by a moderate increase in calcium in the diet. It would also be wise to get at least 400 units of vitamin-D daily to insure proper absorption of the calcium from the tract into the body where it can be utilized."

" When the body does not get enough calcium, it will withdraw what little calcium it has from the bones to make sure there is enough in the bloodstream, then the body does its best to bolster the sagging architecture by building bony deposits and spurs to reduce movement and limit activity."


"Breathing Easy", by Lendon Smith, M.D., in the book
Feed Your Kids Right, Dell Pub. Co. Inc., 1979.

"Calcium is required all our lives for bones, teeth, muscle, nerve function, and for blood clotting. Muscle pains, cramps, twitches and even convulsions may suggest calcium deficiency.” “For asthma, 1000 milligrams of calcium should be given daily along with 1000 units of vitamin-D for intestinal absorption. Calcium can relax the muscle surrounding the bronchial tubes while altering the permeability of the cell walls, allowing the nutrients to get in."


"The Prime Cause and Prevention of Cancer", Otto Warburg,
Lecture at the meeting of Nobel Laureates, June 30, 1966 Director, Max Planck Institute for Cell Physiology Berlin.

"There is no disease whose prime cause is better known, so that today ignorance is no longer an excuse that one cannot do more about prevention of cancer. But how long prevention will be avoided depends on how long the prophets of agnosticism will succeed in inhibiting the application of scientific knowledge in the field of cancer. In the meantime millions of men and women must die of cancer unnecessarily." (Note: in 1966 cancer struck 23% of Americans, whereas today it strikes 39% of Americans).


"The Role of Calcium in Biological Systems", Volume I,
1985, CRC Press Inc.

The Role of Calcium Biological Systems is a compilation of dozens of scientific publications by academically recognized scientists. This book deserves particular note because world class scientists are concluding that there is a link between calcium deficiency and cancer. Also, the hundreds of scientific references contained in this book, as well as the other books quoted, could lead the reader to thousands of scientific publications on the importance of biochemical calcium. Although the first quote is self-explanatory, the second quote may be difficult for the reader to understand. Basically, it says that calcium deficiency in the body fluids outside and inside of the cell stimulates the proliferation of both virus and cell mutation (cancer) by regulating DNA synthesis. Furthermore it concludes that calcium deficiency is the universal property of all cancer cells, the knowledge of which may be the key to understanding cancer.

"Calcium must certainly be the major bioelement of the times. Only a generation ago the calcium ion was known to physiologists and biochemists as a component of bone mineral and as a blood plasma constituent required in heart function and blood coagulation, but little more. But, in the 1970's a crescendo of calcium ion research developed. Today we know dozens if not hundreds of different cellular and extra cellular processes that are regulated by the changes in cytosolic or extra cellular calcium ions. Indeed the calcium ion is emerging as a most important and ubiquitous intracellular messenger" (Forward, Albert Lehniger, Professor of Medical Science, John Hopkins University).

"As we have seen, calcium is central to the ordered progression of replicating cells through their growth-division cycle. Neoplastic epithelia and mesenchymally derived cells can initiate DNA syntheses and proliferate normally in a low calcium medium, which does not support the proliferation of their normal counterparts. Besides needing calcium ions, normal cells must adequately spread out on a solid substrate before they are able to initiate DNA syntheses. Calcium is specifically required for spreading. Lowering the extra cellular calcium and preventing spreading both block the initiation of DNA synthesis, without stopping on-going DNA synthesis. The elimination of extra- cellular calcium requirement for proliferation of viruses can be mimicked by exposing proliferatively inactive calcium-deprived normal cells to calcium-independent-nucleotide protein kinases located in the plasma membrane. Thus, addition of such subunits to the medium of normal cells causes them to behave like neoplastic cells by initiating DNA syntheses in calcium deficient medium. It is clear that the proliferative calcium independence in vitro is a universal property of neoplastic cells, the understanding of which may be the key to understanding cancer." (page 158, Volume #1)


"Calcium in the Action of Growth Factors",
by W.H. Moolenaar, L.K. Defize, and s. W. Delaat, 1986 Calcium and the Cell, 1986, Wiley.

"Proliferation of cells in vivo is regulated by polypeptide growth factors. Binding of growth factors to their specific cell-surface receptors initiates a cascade of biochemical events in the cell which ultimately leads to deoxyribonucleic acid (DNA) synthesis and cell division. The immediate consequences of receptor activation include a sustained increase in cytoplasmic pH and a transient rise in cytoplasmic free calcium ions. The platelet derived growth factor induced calcium ion signal is due to calcium ion release from intracellular stores, whereas the epidermal growth factor seems to activate voltage independent calcium channel in the plasma membrane. These results suggest that the rise in calcium ions is indispensable for cell proliferation."


"Calcium and Cell Function", Volume VII, Wai Yui
Cheung, 1987 Academic Press Inc.

"The regulation of mitosis and cell division is one of the fundamental questions of cell biology. Calcium has been implicated as a regulatory factor in both."


"History of Calcium-Binding Proteins", in the book
Calcium Binding Proteins, by Marvin P. Thompson, CRC Press 1988.

"Calcium has been recognized as a major regulatory ion in all living organisms." "Considering the wide variety of calcium binding proteins in the cell, the potential targets of calcium-related disorders are enormous.” "General interest in calcium binding proteins is still in the logarithmic phase with daily discoveries of these proteins.”


"Intracellular Calcium Regulation", Felix Bronner, 1990, Wiley.

"One of the astonishing developments in biological research is the recent widespread interest in the role played by calcium in cellular metabolism." “Intracellular calcium regulation will be of interest to researchers and graduate students in the areas of biochemistry, biophysics, cell rheology and nutrition."


"The Calcium Connection", Dr. Cedric Garland and Dr.
Frank Garland, 1989, Foreside, Simon and Shuster Inc.

"Low cancer areas were far more frequent in the sun belt. (This statement is contrary to the incorrect popular belief that sunshine causes cancer). What was the significance of sunlight with regard to cancer rates? Sunlight reacts with cholesterol inside and on the surface of the skin to create vitamin-D. Vitamin-D helps the body absorb calcium and plays a major role in the body's ability to use the calcium that is available."


"The Calcium Signal",
Scientific American, November 1987, by Emesto Carafoli and John T. Penniston:

"A common trigger precipitates biological events as diverse as the contraction of a muscle and the secretion of a hormone. The trigger is a minute flux of calcium ions."

"To control cellular process effectively, calcium itself must be regulated. Knowledge of these intricacies (elaborate system of proteins that interact with the calcium ion regulating intracellular messages) may lead to greater clinical control over intracellular calcium, a possibility that has broad implications for the treatment of disease."


"Calcium Homeostasis: Hypercalcemia and Hypo-calcemia",
1986, Gregory R. Mundy, Professor and Head, Division of Endocrinology and Metabolism, University of Texas.

"A number of important metabolic processes are influenced by small changes in extra cellular ionized calcium concentration. These include,' (a) the excitability of nerve function and neural transmission, (b) the secretion by cells of proteins and hormones, and other mediators such as neurotransmitters, (c) the coupling of cell excitation with cell response (for example, contraction in the case of muscle cells and secretion in the case of secretory cells), (d) cell proliferation, (e) blood coagulation, by acting as a co-factor for the essential enzymes involved in the clotting cascade; (I) maintenance of the stability and permeability of cell members, (g) modulation of activity, in particular those enzymes involved in glycogenolysis, gluconeogenesis, and protein kinases which are calcium dependent; and (h) the mineralization of newly formed bone."


"Calcium in Synaptic Transmission", by Rodolfo R.,Scientific American, October 1982.

"The connection between the electrical activity of the cell and the release of the neurotransmitter is not direct; an essential intermediary is the calcium ion."


"Treatment of Vertebral Osteoporosis", by Dr. Meunier in the book
Molecular and Cellular Regulation of Calcium and Phosphate Metabolism, 1990 Alan R. Liss Inc.

"When calcium and vitamin-D is given in daily doses along with moderate amounts of sodium fluoride to patients with osteoporosis, there is a substantial increase in bone mass and a significant reduction in the incidence of further vertebral fractures."

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